Substance

Voriconazole

Brand name:
Vfend

Description

 
Antifungal
 
The drug is prescribed for invasive aspergillosis; severe invasive forms of candidal s (including Candida krusei); candidiasis of the esophagus
Brands:
Vfend And Vfend IV
Availability:
Prescription needed
Pregnancy:
Consult a doctor
Alcohol:
Not detected with light alcohol consumption
Side Effects:
QT Prolongation, Liver Impairment, Urinary Obstruction
Interactions:
Tacrolimus, Prednisone, Bactrim (sulfamethoxazole / Trimethoprim)
For informational purposes only. Consult your local medical authority for advice.

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Before taking Vfend

You should not take Voriconazole if you are allergic to voriconazole.

Some medicines can cause unwanted or dangerous effects when used with Voriconazole. Your doctor may need to change your treatment plan if you use any of the following drugs:

  • carbamazepine;

  • cisapride;

  • efavirenz;

  • pimozide;

  • quinidine;

  • rifabutin, rifampin;

  • ritonavir;

  • sirolimus;

  • St. John's wort;

  • certain barbiturates (mephobarbital, phenobarbital); or

  • "ergot" migraine headache medicines (dihydroergotamine, ergotamine, ergonovine, methylergonovine).

To make sure Voriconazole is safe for you, tell your doctor if you have ever had:

  • heart disease;

  • a heart rhythm disorder such as long QT syndrome;

  • high or low levels of calcium, potassium, or magnesium in your blood;

  • liver or kidney disease; or

  • trouble digesting sugar or dairy products (the tablets contain lactose).

Do not use Voriconazole if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are using Vfend.

It is not known whether voriconazole passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Voriconazole is not approved for use by anyone younger than 12 years old.

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